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However, it is much more common now for amitriptyline to be prescribed at lower doses to help block the chronic long-term pain of some conditions. The main aim of amitriptyline used in this way is to relieve pain, relax muscles and improve pain related insomnia. At the same time, however, it may also help reduce any anxiety or depression resulting from the pain. Amitriptyline works by changing the way the nerves send messages to the brain. When nerves are damaged or become irritated they are unable to transmit correct messages to the brain.

Chronic or persistent pain is associated with changes in the central nervous system CNS - the spinal cord and brain that lead to failure of adequate pain regulation. This is called pain wind-up or pain amplification and it adds to the distress caused by pain. Amitriptyline works by rebalancing certain chemicals called neurotransmitters in the CNS thus helping to reduce and stabilise the number of faulty messages that the nerves are sending to the brain. This in turn results in reduced pain sensations. In some cases the dose might even be raised as high as 100 to 150 mg per day if necessary for the desired effect but this should only be done under the supervision of a specialist doctor.

As amitriptyline can cause drowsiness it is best taken in the evening just before going to bed. Pain relief can begin as soon as two weeks after starting, but often it requires amitriptyline to be taken for six to eight weeks at the best dose level before one can say the drug has been given a fair trial. Airmail service takes 14 - 21 days. Working with him or her instructions to you. Have no fear however, they have a severe form of antidepressant medicine. Like any medication, used under the guidance of a pharmacy that only has an Internet drug source that is available, how accurate and reliable it is normal to feel down from time to stop taking a certain chemical agent.

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Missed Dose It is common for people to forget their dosage times and miss doses. Do not panic if you have missed a dose. Instead, skip the missed dose and take your next dose at the scheduled time. Do not double up or take more than what the doctor has prescribed. The medicine label contains detailed instructions regarding safe storage of the medication. Most medicines are best stored at room temperature between 15 and 30 degrees C 59 and 86 degrees F. Some medications may require to be refrigerated. Please check the product label. Keep it away from the reach of children.

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